What’s Vulnerable › Vulnerabilities

CVE-2025-10937: Oxford Nanopore Technologies MinKNOW Improper Check for Unusual or Exceptional Conditions

• Severity: medium (CVSS 5.5 v3.1)
• Exploited in the wild: not listed in CISA KEV
• EPSS: 0.2% probability of exploitation in the next 30 days
• Public exploit or detection template: none known
• Published: 2025-10-23 · updated 2026-10-08
• Weakness: CWE-754

Description

Oxford Nanopore Technologies' MinKNOW software at or prior to version 24.11 creates a temporary file to store the local authentication token during startup, before copying it to its final location. This temporary file is created in a directory accessible to all users on the system. An unauthorized local user or process can exploit this behavior by placing a file lock on the temporary token file using the flock system call. This prevents MinKNOW from completing the token generation process. As a result, no valid local token is created, and the software is unable to execute commands on the sequencer. This leads to a denial-of-service (DoS) condition, blocking sequencing operations.

Affected products

• Oxford Nano Technologies MinKNOW: before 24.11 — fixed in 24.11

How to fix

Upgrade to a fixed version: Oxford Nano Technologies MinKNOW 24.11. Check the vendor advisory for mitigations.

References

• https://github.com/cisagov/CSAF/blob/develop/csaf_files/OT/white/2025/icsma-25-294-01.json
• https://nanoporetech.com/about/contact
• https://nanoporetech.com/software/
• https://www.cisa.gov/news-events/ics-medical-advisories/icsma-25-294-01

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