CVE-2025-12922: OpenClinica Community Edition CRF Data Import ImportCRFData path traversal

Severity: high (CVSS 8.8 v3.1)
Exploited in the wild: not listed in CISA KEV
EPSS: 0.6% probability of exploitation in the next 30 days
Public exploit or detection template: none known
Published: 2025-11-10 · updated 2026-10-07
Weakness: CWE-22

Description

A vulnerability was found in OpenClinica Community Edition up to 3.12.2/3.13. This affects an unknown part of the file /ImportCRFData?action=confirm of the component CRF Data Import. Performing manipulation of the argument xml_file results in path traversal. The attack can be initiated remotely. The exploit has been made public and could be used. The vendor was contacted early about this disclosure but did not respond in any way.

Affected products

OpenClinica: 3.12.2, 3.13

References

https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-rce.md
https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-rce.md#raw-requests-abridged
https://vuldb.com/?ctiid.331642
https://vuldb.com/?id.331642
https://vuldb.com/?submit.680873
https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-rce.md
https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-rce.md#raw-requests-abridged

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