What’s Vulnerable › Vulnerabilities

CVE-2025-21397: Microsoft Office Remote Code Execution Vulnerability

• Severity: high (CVSS 7.8 v3.1)
• Exploited in the wild: not listed in CISA KEV
• EPSS: 0.8% probability of exploitation in the next 30 days
• Public exploit or detection template: none known
• Published: 2025-02-11 · updated 2026-06-17
• Weakness: CWE-416

Description

Microsoft Office Remote Code Execution Vulnerability

Affected products

• Microsoft 365 Apps: all versions
• Microsoft Office LTSC for Mac 2021: 2021, 2024
• Microsoft 365 Apps: from 16.0.1 before https://aka.ms/OfficeSecurityReleases — fixed in https://aka.ms/OfficeSecurityReleases
• Microsoft Office LTSC 2021: from 16.0.1 before https://aka.ms/OfficeSecurityReleases — fixed in https://aka.ms/OfficeSecurityReleases
• Microsoft Office LTSC 2024: from 16.0.0 before https://aka.ms/OfficeSecurityReleases — fixed in https://aka.ms/OfficeSecurityReleases

How to fix

Upgrade to a fixed version: Microsoft 365 Apps https://aka.ms/OfficeSecurityReleases; Microsoft Office LTSC 2021 https://aka.ms/OfficeSecurityReleases; Microsoft Office LTSC 2024 https://aka.ms/OfficeSecurityReleases. Check the vendor advisory for mitigations.

References

• https://msrc.microsoft.com/update-guide/vulnerability/CVE-2025-21397

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