What’s Vulnerable › Vulnerabilities

CVE-2026-100846: MONAI before 1.5.2 Remote Code Execution via Pickle Deserialization

• Severity: high (CVSS 8.8 v3.1)
• Exploited in the wild: not listed in CISA KEV
• EPSS: 0.4% probability of exploitation in the next 30 days
• Public exploit or detection template: yes
• Published: 2026-09-27 · updated 2026-10-08
• Weakness: CWE-502

Description

MONAI before 1.5.2 contains a deserialization of untrusted data vulnerability in the algo_from_pickle function in monai/auto3dseg/utils.py. The function reads a .pkl file and passes its contents to pickle.loads without validating the data source or content. If an application invokes algo_from_pickle on an attacker-supplied pickle file, an object defining __reduce__ is executed during deserialization, resulting in arbitrary code execution in the context of the application.

Affected products

• Project-MONAI MONAI: before 1.5.2 — fixed in 1.5.2

How to fix

Upgrade to a fixed version: Project-MONAI MONAI 1.5.2. Check the vendor advisory for mitigations.

References

• https://github.com/Project-MONAI/MONAI/security/advisories/GHSA-89gg-p5r5-q6r4
• https://www.vulncheck.com/advisories/monai-before-1.5.2-remote-code-execution-via-pickle-deserialization
• https://github.com/Project-MONAI/MONAI/security/advisories/GHSA-89gg-p5r5-q6r4

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