What’s Vulnerable › Vulnerabilities

CVE-2026-109361: MONAI 1.2.0 before 1.6.1 Insecure Deserialization RCE via nnUNetV2Runner postprocessing_file Path

• Severity: high (CVSS 7.3 v3.1)
• Exploited in the wild: not listed in CISA KEV
• EPSS: 0.2% probability of exploitation in the next 30 days
• Public exploit or detection template: none known
• Published: 2026-10-12 · updated 2026-10-26
• Weakness: CWE-502

Description

MONAI 1.2.0 before 1.6.1 contains an insecure deserialization vulnerability in nnUNetV2Runner that unpickles the postprocessing_file path read from inference_information.json without confining it to the results directory. Attackers who can modify inference_information.json can point it at a malicious pickle elsewhere on the filesystem to execute code when predict_ensemble_postprocessing runs.

Affected products

• Project-MONAI MONAI: from 1.2.0 before 1.6.1 — fixed in 1.6.1

How to fix

Upgrade to a fixed version: Project-MONAI MONAI 1.6.1. Check the vendor advisory for mitigations.

References

• https://github.com/Project-MONAI/MONAI/commit/08576205c4de3c214976294d1dec8f7b2e78cdb9
• https://github.com/Project-MONAI/MONAI/security/advisories/GHSA-8f32-8649-rv87
• https://www.vulncheck.com/advisories/monai-1.2.0-before-1.6.1-insecure-deserialization-rce-via-nnunetv2runner-postprocessing-file-path

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